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Old 07-22-2010, 04:37 PM #2
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb

Topamax can alter the excretion of bicarbonate, and hence it also may cause kidney stones.

A warning letter was sent to doctors several years ago to watch for low serum bicarb in patients.

http://docs.google.com/viewer?a=v&q=...s_9ecvDzikYVow

Acidosis leads to altered feelings in the periphery... called paresthesias.

Other anti-seizure drugs do not have this effect on the kidneys.
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