I don't think the Rocephin has been implicated in PN.

But Strep infection involves protein sequences on the strep cell wall that are similar to some human tissues. PANDAs...is a CNS movement disorder that occurs in children who have strep. The antibodies in our blood stream target the strep and also US.

When the infection clears up, you may find the nerve effects may lessen.

Do a Google search on PANDAs and learn more about how this happens if you want.

Do you know how this happened? Have you had injections back there?

You can do the 2500 mcg ... as I said it is benign. Just take it on an empty stomach for best absorption and results.

I am not knowledgable about some of what you asked. I think it is important to ask your doctor. I remember in the start I was nervous to but now I come up with a note pad and binder. You deserve to get your concerns and questions answered. I would also ask the doctor if they feel this infection could be impacting your nerves and get their thoughts on that.
I always fear things making me worse since it has happened so now I ask my doctor what will happen if it makes me worse or will it. Then I try to weigh th pros and cons and stay in the moment. The worry,anxiety,and fear does not help in this condition. Easier said then done to not though and those 3 words are a huge part of me. I am really working on relaxing though.
Hope you feel better

i dont know how long you have had PN symptoms but it is also possible to have large fiber PN and it not show up on an EMG/NCS for a while until the damage becomes sufficient to be measurable by those tests.

Echos long ago, what were your first symptoms of large fiber PN?

my first symptoms were numbness in the big toes. next was pain when standing too long or wearing shoes for too long.