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Old 08-24-2011, 07:42 AM #1
glenntaj glenntaj is offline
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Default As Gabapentin--

--and Pregabalin (Lyrica) are both excreted almost whole through the kidneys and not appreciably metabolized through liver enzymes, the rates at which people "clear" these drugs (or, to put it another way, their "half-lives") vary considerably from person to person, and I've certainly seen people prescribed doses divided up in different ways--twice a day, three times, four times. Often some experimentation is needed to see what works best for the individual.
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Old 10-19-2011, 08:02 PM #2
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--and Pregabalin (Lyrica) are both excreted almost whole through the kidneys and not appreciably metabolized through liver enzymes, the rates at which people "clear" these drugs (or, to put it another way, their "half-lives") vary considerably from person to person, and I've certainly seen people prescribed doses divided up in different ways--twice a day, three times, four times. Often some experimentation is needed to see what works best for the individual.
Just a quick update, I have changed my meds toGabapentin 8am- 900mg, 4pm- 600mg and 10pm- 900mg, I have kept my cocodamol at 10am,2pm,6pm and 10pm.
This is now ideal timing for me and I am in a lot less pain.
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Old 09-10-2012, 03:37 PM #3
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Just a quick update, I have changed my meds toGabapentin 8am- 900mg, 4pm- 600mg and 10pm- 900mg, I have kept my cocodamol at 10am,2pm,6pm and 10pm.
This is now ideal timing for me and I am in a lot less pain.
I was told my GP that cocodamol was no good for nerve pain so I stopped taking it. Might have to start it again!!!!! I'm on 2100mg Gabapentin per day plus 2 Amytryptiline at night but I am still in pain so I'm upping it by 600mg thro 1 week. The max I have been told by my doc I can take is 3600mg per day
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Old 09-11-2012, 06:31 AM #4
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I was told my GP that cocodamol was no good for nerve pain so I stopped taking it. Might have to start it again!!!!! I'm on 2100mg Gabapentin per day plus 2 Amytryptiline at night but I am still in pain so I'm upping it by 600mg thro 1 week. The max I have been told by my doc I can take is 3600mg per day
It was conventional wisdom for doctors to say that opiates don't help nerve pain, but recent studies have contradicted that. Many people with PN pain are on a combination of gabapentin or Lyrica, an opiate, and possibly an anti-depressant.
If you have severe pain, not just the burning, zapping kind, I don't think maxing out your gabapentin will help. For myself, it only seems to help with the burning, zaps, and hamsters running all over my feet and legs. It does not remove those sensations entirely, nor does it touch the crushing, twisting type of pain. Was the cocodamol helping?

Last edited by Susanne C.; 09-11-2012 at 06:59 AM.
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