I was wondering about the safety of these in Neuropathy. I might be starting two them after seeing my doctor. I think part of my POTS is Mast Cell Activation. H1 and H2 blockers might be needed.

I was wondering about Claritin, Zyrtec, Zantac, Tagmet and Pepcid. Any bad for neuropathy. I might only need Claritin, but I may need to add one of the others, H2 blocker.

I try to never take meds so I am nervous.

I just finished a week of Duricef for a UTI. Even though I was doing all I could not to get one again. Just happens I guess. I was taking Dmannose and cranberry supplement. Lots of water of course.

Anyway, I hate meds since they are not good for me but sometimes there is no choice. Just wondering about these.

--is advised, at the very least, to consider B12 supplementation, as the reduction in acid concentration these engender makes it much harder to break B12 out of food, which gets harder with age anyway.

I also think, since acid is necessary for protein to be released from foods, that one should try to monitor this and eat a somewhat lower carb, higher protein diet. This doesn't have to necessarily come from animal products--proper combination of grains and legumes/vegetables can provide it. There seems to be more difficulty breaking protein out of animal products with low stomach acid.

I think Claritin is very weak and mostly useless.

I use Zyrtec at night and sometimes rotate with Benadryl if it stops working.

I use them for my allergies. Spring and fall mostly but sometimes to help sleep too.

When I need it, I use Tagamet OTC 1 or 2 of those. But one has to be careful with Tagamet if using RX drugs. Many drugs interact with it. I don't use much and my blood pressure drug is not metabolized by the liver so that is okay for me. But I think Tagamet is the most efficient. If I have to I use it only at night.

One of my water fitration Brita pitchers developed algae in it!
That has never happened before. Just before I could see it, I started getting heart burn like I do upNorth! I had to take Tagamet for a WEEK... once we realized what was happening, I nuked the pitcher with bleach and the heartburn is now gone!

When people have severe allergies to food and/or drugs
an H2 blocker is often given with the antihistamine. This happens too with premedication for IV dyes and CAT scans etc.
Has to be Tagamet or Zantac, or Pepcid or Axid.
Proton pump drugs like Prilosec don't work on Histamine receptors.

The potency of antihistamines for allergy go:

Atarax>Benadryl>Zyrtec>chlopheniramine>Allegra>Cla ritin

Claritin requires activation by the liver to active metabolites, and that can take 3 hrs or more. And it can also raise liver enzymes in some people.

I think if you only use the H2 antagonists very occasionally, not much effect on nutrient absorption will occur. It is daily use for long periods that begin to affecting B12 and other things seriously.

I'm very drug sensitive and Zantac didn't kill me so you are probably safe. I have COPD and it did make me a little short of breath but I didn't notice any effect on my neiropathy. I only took it for a month though.

I don't remember if I have posted this before but was wondering if you are drinking cholorinated water? I had bladder problems for 25 years, was told the only treatment was lifetime antibioltics, but I have had almost no problems since I put a Pur filter on my faucet. Most of my problems were due to inflammation and I'm not sure if that would play a role in susecptibility to infection but it might be something to try..if nothing else your coffee will taste better.

There is also fluoride in many drinking waters.
There are many anti-fluoride sites on the net...I am on the fence with it still.

People using a well, can have natural arsenic build up along with
many other nasties. So using a filter these days is a good idea.

Mast cell activation is more than allergies, the meds can be the same though. It can cause POTS. My integrative MD says my POTS is caused by Autonomic Neuropathy. I think I also have the other problem.

I take b12 daily and my blood is tested twice a year for that and many things. I have a wonderful regime of supplements each day for my POTS, PN and CFS.

I just wanted to make sure all of the meds are not bad or cause neuropathy. I am healing and do not want anything to interfere. I try to never take meds.

I will talk to my doctor Monday.

I also have HistaEza. My integrative MD likes it for allergies. I hope he will say it will help mast cell activation. That would be great! Natural ingredients.

I have a Berkey filter. SO good. Pretty too.

I was just wondering if anyone has tried any of these. I had a problem with Claritin so the others will be very much the same. I called the pharmacist and most are about the same. I want to try an H1 blocker first, then add h2 like Zantac. Both need to be used for Mast Cell activation. I talk to people with POTS and Mast cell online and everyone has one they take, but many do not have the autonomic neuropathy I have to be careful with. If I ever find something I can take I think I will improve furthere.

I am using Quercitin and Nettles by Designs for Health right now. I may need to use it for a longer time to see if it will be what I need but so far, it is not enough.

This isn't allergy, it is dermotographia, itching, severe flushing, Orthostatic intolerance, problems with vasular tone=pooling of the blood so it is not able to stay in the heart and brain.. nothing with eyes, nose etc.

I think I will talk to my doctor and add another supplement to my Quercitin and Nettles. More are listed here.

http://www.mastcellmaster.com/docume...heoharides.pdf

There is a thing that happens to some older people. The H2 antagonists, like Zantac, Pepcid can cause CNS symptoms of headache and/or delirium in the elderly. This is often dose dependent, however.

It has to do with crossing the blood brain barrier which sometimes erodes in the elderly.

So that would not be a problem until I am older?