I'm no expert by any means but I would assume that weight loss would be a positive thing for someone that is overweight and has PN. Especially if is caused by a metabolic or compression issue. I have heard that being overweight can cause an unhealthy posture and spine which could cause or exacerbate PN symptoms.

The odd thing is that me and other people here had mentioned that PN started after losing weight, so it might seem that the weight loss could be somehow trigger it .
As I said in another thread, could it be that the losing weight disrupts the balance that the organism used to have about glucose handling because, say, now glucose gets higher because it has to be shared by a smaller body than before? less cells to feed? or there are now less adipocytokines andso the metabolism gets altered?
Pure speculation, but hey, if I know one thing is that biology is all about checks and balances.
(No that I would suggest trying to gain weight again to see if one restores the balance..).

Of course, it could be just a coincidence, no relation whatsoever, we were going to develop PN anyway, regardless of the weight loss.

Losing weight can have other triggers.

If you have fat soluble toxins stored in your fat, then when that fat dissolves it releases them...which may irritate nerves.

Also there is a possibility of harming self repair of nerve cell walls, etc, when eating a low fat diet. There is even a term for this, called "slimmer's paralysis" that can be found in some medical papers. Certain omega-3 and omega-6 fatty acids are needed by the body (they are essential) to maintain and repair the nervous system. So people eating really low-fat for a period of time, could create problems with maintenance of nerves.

Dieting can also encourage low blood sugar periods which are problematic, and starve cells.

Jeez...why does everything have to be so darn complicated? I want to lose weight but I also don't want to release toxins or starve cells.

It has to do with balance, and what you eat. You can lose weight, perhaps a bit more slowly, by allowing essential fatty acids to be consumed. Very low fat diets have been recently discarded. The fats typically recommended to be avoided are high intake saturated fats, or too many Omega-6's.


I don't know how to deal with the toxins released from the fat however.

I'm thinking maybe drink a lot of water!