In the thread below last year someone posted about a supplement called Normast and how it helps various types of nerve pain.


http://neurotalk.psychcentral.com/sh...hlight=normast



It's still only sold oversea's but wondering if anyone has tried it? It looks legit.

http://www.painkillernormast.com/slide-view/research/

Lots of things look Legit. I looked at this in the past, and it
does not look like it is a serious risk. I believe you have to
send to Italy for it. But that have changed.

I have not seen a review on it either. One would think by now if it were a great thing, it would be more available and more talk about it.

There is a new website on this, and it seems the supplier has moved to Netherlands. It does seem too good to be true, however.

http://www.youtube.com/watch?v=EN1t9...eature=related
http://www.youtube.com/watch?v=jFle7...7&feature=plcp

A few minutes ago. I am thinking about trying it.

Also, a study with this combined with Lyrica helped as well.
http://www.youtube.com/watch?v=c5bGCiruQUM

pay close attention after 14:35. Sounds like this has very high success rate.

http://www.youtube.com/watch?v=SVD3l968Ck4

Try this reference:
http://en.wikipedia.org/wiki/Palmitoylethanolamide

It appears that PEA works on cannabinoid systems (marijuana).

Not much in the way of human trials however, and they were small, and required at least 2 months to see effects.

I could not find anything "alarming" about this substance but I remain guarded that it will actually work. Also on their main website was a fellow who had his confiscated by customs. Then the supplier claims..."all fixed".

I am slowly watching this video...the 3rd link in your post.
The presenter is going very fast... but I just saw him say...
PEA is effective in MULTIMODAL use...meaning used with other treatments. Also I am getting the feeling you will need to take it all the time. That its effects will wear off if you discontinue. But I am still watching...I have on pause now to have some breakfast.

If you believe the YouTubes (and there are many on the net with "believeable" things), nothing is stopping you from trying it.
I try things after long consideration myself, and some have been very successful for me. You could be our first guinea pig with Normast!

Also the study in this video and the topic involved sciatic pain. Keep that in mind. Allodynia may be different.

There are some new postings on the net regarding low dose Benadryl (5mg every 4-6 hrs) as suppressing inflammation due to MS (improving functions). It is thought that it reduces inflammation of mitochondria, at this time.
It is about 1/2 teaspoonful of children's liquid Benadryl. Since it seems to work for MS lesions, it may help with other nerve inflammatory problems.
That video showed some histamine receptors in the glial as possibly problematic.

Treatments aimed at targeting the Glia is what Nancy Sajben MD believes is the future.

http://painsandiego.com/2012/01/29/g...eatment-fails/



I also found a powerpoint on it.

http://prezi.com/zwefx9bmle96/palmit...of-of-concept/

Today's post talks about a product, supposedly for neuropathy, that is promoted and sold from a source in the Netherlands. It's called Normast and it seems many people across the world, especially in America have been persuaded to buy it in the hope of helping their neuropathic problems. The website will try to persuade you by using incredibly complex language, that it's based on good science and research but in fact it's nothing more than (at best) a homeopathic product, with less than 1% of the palmitoylethanolamide it claims underpins it. the Dutch authorities have refused to give it a license as a medicine and for want of anything better, only allow it to be described as a food supplement.

You can look up Normast on the web and you will probably see links to a dutch website and one run by Ergomax.

It is promoted by Prof. Dr. Jan M. Keppel Hesselink, who's self-proclaimed title of professor is not recognised by the Dutch authorities. He also claims to be a pharmacologist and medical biologist but is also not registered in the Netherlands. He also claims to be linked to a medical university in Germany, which is bankrupt and furthermore does not have him on their employment lists. The best anyone can establish is that he is an unlicenced acupuncturist.

He sells Normast through a company called Ergomax or you may see it sold from an Italian company Epitech.

The problem is that much of the information about neuropathy on the sites is true and in some cases helpful, as information. He also sells Alpha Lipoic acid and Acetyl L- Carnitine amongst others, which are legitimate supplements known to have helped some people with neuropathy. So, just as with many of this sort of 'preparations' for neuropathy, there is a half accurate story to convince the buyer that the promoters are genuine but there is absolutely no scientific evidence that Normast works.

The Dutch Association which investigates quacks and charlatans have roundly condemned this man many times and if you look on the various independent forums about Normast, you will see many complaints that people have lost their money for nothing. Mister Keppel Hesselink or someone known to him, writes his own questions and answers (all positive of course) for various forums and has many YouTube video clips (in broken English) which are based mainly on patient accounts.

Of course, everyone must make their own minds up about Normast but this blog feels it necessary to take the opportunity to warn people about likely disappointing results. Do your own research and you will probably reach the same conclusions.

*edit* i only include this tips because whenever you make claims and counter claims, you need evidence to back them up.

When people are desperate due to neuropathy pain, they will clutch at any semi-convincing straws but should be aware that there are many unscrupulous operators on the internet and should research anything claiming to be a 'new' cure or 'help' for neuropathy. If the top neurologists and pharmaceutical companies have failed to come up with effective treatment when all accepted medications have failed, it's highly unlikely to be found by a private source which tries to sell it to you over the Net.

Welcome to NeuroTalk, Drew.

Do you have any evidence that the product which claims to have either 600mg per dose, or 300mg per dose only contains 1% of that claim?

Many things claim to be homeopathic in US, and use higher than homeopathic doses. The true definition of homeopathy can become quite clouded here.

I have my doubts about this product anyway, so I would like a bit more information, please.

While you cannot link yet, being new, you can give a hint to a Google keyword search for those of us who wish to learn more.

Yes Drew, I was going to possibly order some but will hold off until getting this until I can gain access to some of additional information you have stated.

Hi MrsD and bent98,
It's very frustrating indeed but I can no longer find the page which gave specific details of the make up and ingredients of Normast. They've removed all such 'ingredients' passages from their own websites and Googling everywhere else either brings you back to the Dutch or English language Normast sites (all run by the same person). What I do remember is that the 'active ingredient' palmitoylethanolamide, was less than 1% of the total due to 'micronising' (their word not mine). Now micronising means reduction of the base element as part of the accepted homeopathic preparation process. I'm still trying to track down the active ingredients, or at least evidence of them but am not having any luck at the moment. That in itself should set alarm bells ringing in people's minds - why would you buy something without knowing exactly what was in it?
I hope MrsD, you'll be able to look at the Google translation of the two links in Dutch that I sent you because, despite the bad English that you undoubtedly will see, Google tends to translate to pigeon English) you'll be able to see how the Dutch organisation for investigating quacks and charlatans has come to some very strong conclusions about Mr, Keppel Hesselink and his dubious practices - his claimed qualifications are pretty much fantasy (as those articles show).

As you may have seen from my other post, I am a long term neuropathy sufferer myself and 4 years ago set about collecting as much genuine and expert information in one place about the disease and its treatment, to share with others. This is really to show you the nature of my involvement with neuropathy. In the course of all that research, I've come across various con men and scams in that time (especially in shady clinics in the States) as I'm sure you have. It upsets me greatly when people set out to make money out of the desperation of people with neuropathic pain. People will jump at anything which promises to take their pain away but we all know that nerve damage is not curable (in the long term) and the medications to reduce pain are limited. It is inconceivable that a product such as Normast would have escaped the attention of the major pharmaceurical companies if it were genuine. They're only aim after all is also to make money...but only from successful and tested products (the FDA makes sure of that).
If anyone can find the ingredients and their proportions, or even a number of people who have genuinely benefited from Normast (without having to use other things alongside) and not those on the forums written by keppel hesselink himself, then maybe things will become a little clearer. My neurologist here in Amsterdam is convinced that people who claim to have done well with Normast are showing placebo effects rather than genuine physical improvement and relief from the symptoms.
Keppel Hesselink remains under suspicion here in the Netherlands but like in all bureaucratic systems, the wheels of change move very slowly, so it may be some time before he is forbidden to practise. He can't be struck off the register because he isn't on one - he is only a self proclaimed acupuncturist here in this country and is not recognised as a professor, or as holding a chair in medical pharmacology at a German university. Proof of this is in those two Dutch links I included last time - sorry MrsD, I realise this is putting the onus on you but you need genuine proof and my translating them, is not convincing enough i fear.

I just feel that people should be very careful about ordering Normast - don't believe all you read and do your own research (outside the company's own sites). If you can't find anything then that should be suspicious enough. Having said that, from what I can see, Normast will not do direct harm but a homeopathic treatment cannot mend broken nerves and its painkilling properties are doubtful considering that the body makes PEA itself. If we need a supplement, then it first has to be proved that we have a deficiency and Ergomax and Epitech can't do that.