Sorry about that; no offense intended. I'm misunderstood/misconstrued quite often here, myself. I chalk it up to the inadequacies of the medium, but it is the only game in town.

As for damage, I don't know, but you asked for thoughts, and I tend to err on the side of caution. Perusing the articles/studies regarding acetaminophen & alcohol, it's being found that while either used alone in moderation may be ok, combining the two with even "small doses" of acetaminophen or "light amounts" of alcohol may be enough to instigate damage. It's the mixture.

I can't take NSAIDs, so when I began taking acetaminophen for chronic pain (many years ago—long before PN), I did 2 things:

1. I began taking NAC daily to mitigate damage to my liver & kidneys.
   (and I recommend this to anyone who takes acetaminophen—or meds containing it—e.g. Percocet, Tramacet, etc.—daily)
2. I stopped drinking alcohol—haven't touched it in ~10 years.

Doc

Thanks for all the thoughts on this, and yes I appreciate ALL of them. I am luckily in that I can sit all day at my job and with good insoles and my cane I can walk to and from my car without medication. So, I only take my Tramacet on weekends when I have to shop. Even though I wasn't taking it daily, I had cut back my alcohol intake and now I think I will cut it back even more. Not sure what I will do with all my nice bourbon and scotch.