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Old 01-06-2017, 10:50 AM #1
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Thank you for the link Mrs D. I will do some more research before purchasing.
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Old 01-06-2017, 01:06 PM #2
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Here is a study done on animals that shows the micronized forms working better than non-micronized forms. (2014)

Micronized/ultramicronized palmitoylethanolamide displays superior oral efficacy compared to nonmicronized palmitoylethanolamide in a rat model of inflammatory pain

So solubility IS a factor, and if anyone here wants to try this PEA, then I'd suggest you get the micronized version.
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Old 01-07-2017, 03:50 PM #3
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I mostly work on large Phase III clinical trials. I've seen Normast listed as a concomitant medication for a handful of European patients. The indication was listed as pain if I remember correctly. I've always wondered it truly helped.
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Old 01-07-2017, 06:00 PM #4
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This case series and the references cited in the paper may be of interest Therapeutic utility of palmitoylethanolamide in the treatment of neuropathic pain associated with various pathological conditions: a case series.
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Old 01-09-2017, 07:38 AM #5
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Quote:
Originally Posted by mrsD View Post
Here is a study done on animals that shows the micronized forms working better than non-micronized forms. (2014)

Micronized/ultramicronized palmitoylethanolamide displays superior oral efficacy compared to nonmicronized palmitoylethanolamide in a rat model of inflammatory pain

So solubility IS a factor, and if anyone here wants to try this PEA, then I'd suggest you get the micronized version.
Happy New year! I hope it's a better one for all us here.

Given what's been written on this subject would there be a recommended brand if one wished to give this a trial run?

Thank you kindly,

Cliffman
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