I replied to you PM as well, but since you added some stuff here . . .

There are hereditary neural conditions that can "imitate" acquired small-fiber neuroapthies/symptoms and that have predominantly small-fiber effects, although most of them don't have the subacute onset you've described--they tend to come on more gradually.

Still, I would lean towards a small-fiber predominant neuropathy with a possible molecular mimicry autoimmune etiology--you may well have gotten a viral or bacterial infection that your immune system attacked and fought off, but the structure of the pathogen was sufficiently similar to some part of you sensory nerves that the now activated immune system could not distinguish pathogen from self and continued attacking those parts of your nerves. I happen to think this process is more common among people labelled "idiopathic" than most neuros believe.

There are a number of acute/subacute demyelinating neuropathies (inbcluding CIDP variants) that have been associated with previous infection; no reason to assume this could not happen to the axonal fibers as well.

Take a look (at the herediatary areas, especially) at:

http://www.neuro.wustl.edu/neuromusc...ory-small.html

I would think that your doctors could at least look up/try some of the genetic test to "eliminate" known hereditary conditions. I can also say that my QST was normal, but my skin biopsy unequivocally showed small fiber damage--often it depends just WHICH small fibers have been preferentially attacked.

I just got diagnosed with this disease in March of this year but have been battling this for the past 5 years. Been going to see a pain management doc who is treating me like human guinea pig with meds that interact badly with the other meds I am taking. I am 40 years old and do have some back problems due to my military service 20 years ago. I know what it's not linked to diabetes since my blood sugar has been in the normal range.

I am wondering if there is any real cures for this because I don't want to live like many of you who have suffered with this for years. Don't mean to sound disrespectful to anyone here. I am suffering from intense itching and burning on both feet, also my toes are beginning to go numb and at times I am up for more than 24 hrs at a time when I have a major attack during the night.

Hi Majorcut & welcome to the forum, to get more exposure it's really best to post a new thread, but anyway, there are over 200 known causes for PN, it might help if you give more information, like what test's have been done so far besides Diabete's, have you been tested for prediabete's ? what was your b12 levels when tested ?, are you seeing a Neuro that is a PN specialist ? spinal taps, had an MRI on your back ? stuff like that may help.

No neuro at all just a pain management doc who got ****** that I went to my primary care doc for some pain meds when she couldn't be reached after I had a severe attack that last for 2 days. I haven't had a spinal tap and I have been tested for diabetes. So far I am not a diabetic or in pre-diabetic stage. What I have is idiopathic PN which means the docs have no idea on what caused it.

Majorcut,
Please post in a new thread giving your health history. Give us your symptoms, medications, what tests you have had done, etc. There are a lot of extremely knowledgeable people on this forum and we have a huge amount of combined knowledge. Just telling us you are idiopathic isn't going to get you real answers. I was labeled idiopathic until the proper testing was done. I now know what is causing my neuropathy, but it took the proper testing and the right type of doctor to find this cause. There are some answers out there but you have to help us with more than you have given us.

Oh..welcome to the forum. There are good people here.
Billye