I've had symptoms of peripheral neuropathy since May, which at the time, it appeared I had a virus. Not sure if that was a cause, or just what slowed me down enough to really notice my other symptoms. I have numbness/pins/needles/sharp fleeting pains/joint aches/Restless leg syndrome being rx'd w/ Requip. pins/needles/numbness from nose and across jaw line.. hands/feet/arms/legs/sometimes in spine area.

I have had testing of blood for: HIV, STDs, vitamin deficiencies, autoimmune diseases (1st ANA postive 1:1280 all others neg) TSH, blood cultures, urine cultures, kidney function, liver function, CBC, basic glucose levels and basic thyroid levels and on... all normal levels

I have had MRI's of brain w/ and w/out contrast - unremarkable.
MRI of lumbar spine: herniated L5 (knew that since 1992)
MRI of cervical spine: stenosis, spurs, encroachment on nerve sac in C5/6 (If I recall correctly) 2-lesions w/ suggestion of a bone scan

EMG/NCS normal --

toning fork test results: vibration felt for more than 10 seconds

Having a 2 hr glucose tolerance test on Tuesday.

Beginning PT for lumbar and cervical issues.

Has anyone had these test results w/ these symptoms?

I truly feel I am going nuts. I won't medicate beyond the Requip til we figure out whats going on. I have a "need" to diagnose before treating symptoms, it just makes sense to me. I agreed to the Requip because I was NOT sleeping well at all, which added to all my symptoms.

Please.. anyone have any clues about this?

Hi, Welcome

What's your B-12 Level?

B-12 deficiency can cause PN. Read all the posts about it on these forums.

Interesting stuff. Others will jump on board and help you.

that's been tested.. it was fine....

Even so I started taking the B-12 from iherb that you recommended for more than a month now.

I hope someone has an inkling of a clue... because you'll be my hero my drs. don't have one... in three months of testing and examinations.

-though I'd recommend they extend it a few more hours, with measurement, concurrently, of your insulin levels as well as glucose. This is because it is now well-documented that impaired glucose metabolism can result in neuropathy, especially of the smaller fibers that subsume the sensations of pain and temeprature, well before frank diabetes would be diagnosed.

There've been a number of recent posts that list a number of papers and overview on that subject:

http://neurotalk.psychcentral.com/sh...603#post150603

http://neurotalk.psychcentral.com/sh...ad.php?t=27026

Moreover, you sound like could very possibly have a small-fiber neuropathy--and these are often very hard to discover with "standard" testing, but the symptoms--sensory and/or autonomic--can be severe.

Take a look at:

http://www.thecni.org/reviews/13-2-p07-treihaft.htm

http://www.enabling.org/ia/celiac/do...%20article.pdf

http://www.neuro.wustl.edu/neuromusc...ory-small.html

Thanks!!

I will read all of it.. I appreciate your reply!!

HI Babs! I had all those tests and they all came back fine....was a little low on Carnitine and Vit. D. Finally my dr. scheduled a nerve/muscle biopsy and that diagnosed Chronic Axonal Neuropathy......that might talk to your dr. about that. My dr. said a lot of the time it's the only thing that shows what the problem is. Good luck! Roxie