--the way those alarming commercials try to tie high cholesterol levels to heart dsease is a great oversimplification. High LDL levels alone do not seem to have a major coorelation with myocardial events, whereas high levels in conjunction with high homcysteine and C-reactive protein levels do. The other part of the puzzle seems to be inflammation:

http://www.webmd.com/heart-disease/g...in-crp-testing

Of course, I know you've had various inflammation issues over the years, but how are those levels currently? You may, as cycelops says, be able to lower your levels enough with merely diet, exercise, and some supplementation to "live on the cusp".

In terms of cardiac risk: My CRP and homocysteine are always low, and I don't have other risk factors, except a dad with coronary disease. My chol:HDL ratio is still good, even with these very high numbers it's 3/4.

I take my supplements, which should help also: I take AREDS formula antioxidants, as well as alpha lipoic acid, CoQ10, acetyl L carnitine, and N-acetyle-cysteine (which keeps homocysteine down). Oh yes, omega fatty acids.

I had posted on this thread that the sinus guy wanted me to irrigate with Avalox. I was wrong; it's Amikacin. I haven't begun, as I don't have enough information to be comfortable. The mycobacterium is called m chelonae, and I've found just about nothing useful on the web. The cultures are still cooking.

Happy Thanksgiving to all.

The identifying information came in on the organism in my sinuses. It's called mycobacterium cholanae/abscessa, and the recommendation is Doxycycline, Amikacin, and Biaxin for 3 - 6 months. The organisms were grown at Mayo, and in Dallas, but apparently Mayo has never had this in one of its own patients. My doc says he's gotten it in 25 cases, out of 2000 or more patients.

He says the decision about what to do is totally NOT an emergency, so I should just think about it. He had no recommendations for people to talk to, but said whoever I come up with is fine; it's just that no one has experience with this.

wow 3-6 months....after ten days on biaxin for respiratory infections im ready to be finished, but that is at 500mg 2x a day......what are the doses that you would have to take everyday....

Please respond..I too have chelonae siuns infection and would appreciate input from you since you have gone thru the treatment process

Hi--I was put on several antibiotics for about 6 months: Biaxin, Nasal Amikacin, and one other. Within a month I had a new lease on life and felt much better. I've had only one sinus infection since last January, when this diagnosis was made. I have, however, had aphthous ulcers of the throat, which is thought to be due to chronic infection or immunosuppression.

This lead to an immuno w/u and more culturing, and I tested positive for lyme disease, as well as not making immune antibodies of the IgG sort.

So now I am on antibiotics again, which the doctors I am seeing concurring that I have chronic lyme, that the mycobacterium was probably innocent, that many people carry it, and that the reason I felt better was that my lyme was being treated.

Go figger. They say I'm in for another year of antibiotics, and are pushing for IV. I've been pushing back, wanting a bit of a normal life, but I'm pretty sure I'll give in in a month or so. I do not feel anything like the way I did the first few months on antibiotics last year, and it's typical of lyme that antibiotics need to be rotated, because the bacteria changes forms.

I hope treatment helps you, but if it's just sinuses, it may not be the culprit.
My sinus guy who treated it is rare, with most of the other ENT/sinus guys thinking that many people harbor these organisms harmlessly. I don't know, myself.

Good luck.

Thank you for your explanation...I wanted to know how long it took the antibiotics to relieve your symptoms (one week, a month?). Also who was the sinus doc that you went to? I live in NJ..

Thanks for the info..do you remember how long it took the antibiotics to relieve your symptoms... a few days..a few weeks, a month?
What is your Sinus doc''s name..the one who treated you for the chelonae infection..was it Dr Tichenor?

Yes, it's Dr T. see pm