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Old 02-09-2008, 07:42 AM #8
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mrsD mrsD is offline
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Lightbulb more on Vit K...
http://lpi.oregonstate.edu/infocente...mins/vitaminK/

Quote:
Bone mineralization

Three vitamin-K dependent proteins have been isolated in bone. Osteocalcin is a protein synthesized by osteoblasts (bone forming cells). The synthesis of osteocalcin by osteoblasts is regulated by the active form of vitamin D, 1,25(OH)2D3 or calcitriol. The mineral-binding capacity of osteocalcin requires vitamin K-dependent gamma-carboxylation of three glutamic acid residues. The function of osteocalcin is unclear, but is thought to be related to bone mineralization. Matrix Gla protein (MGP) has been found in bone, cartilage, and soft tissue, including blood vessels. The results of animal studies suggest MGP prevents the calcification of soft tissue and cartilage, while facilitating normal bone growth and development. The vitamin K-dependent anticoagulant protein S is also synthesized by osteoblasts, but its role in bone metabolism is unclear. Children with inherited protein S deficiency suffer complications related to increased blood clotting as well as to decreased bone density (6, 7, 9).
Vit K is made in our bowels, and since kmeb has "issues" there, she probably does not. Also it is in green, leafy veggies.
Quote:
Supplements

In the U.S. vitamin K1 is without a prescription in multivitamin and other supplements in doses that generally range from 10-120 mcg per dose (35). A form of vitamin K2, menatetrenone (MK-4) has been used to treat osteoporosis in Japan and is currently under study in the U.S (36)
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