Hello,
I have been struggling with health problems 3 years now, with the main problems being neuropathy, joint pain and extreme fatigue. I recently had a skin biopsy which was negative for small fiber neuropathy. I am confused by this as I have pronuonced sensory loss, parathesia and mild foot drop. Nerve biopsy and emg/ncv are also normal. It is thought that I have vasculitis and some sort of inflammatory polyarthritis. I have been treated with imuran and prednisone for a year, but am still not in remission.

Shouldn't my biopsy have been positive if I have peripheral neuropathy? Can something else cause these symptoms? I am feeling very discouraged as there is little diagnostic proof of my diagnosis and I am not getting better after going through tons of testing.
Laker