Hey Franny-
I'm on Synthroid and Topamax too, and I take my Synthroid first thing in the morning on an empty tummy and then I eat a little breakfast (usually cereal with milk! to protect the tummy!) and THEN I take my other meds. Although, Topamax has never affected my stomach, so are you sure that that's what's doing it? Not to second guess you or anything, but could it be a bug or something? I randomly got nauseous and threw up for a month once. And no- wasn't pregnant! Silly doctors couldn't figure out what was wrong with me, and then a year later when my thyroid hit rock bottom they decided that that was when it originally quit working. So have your thyroid levels checked too. They can really effect your digestion because they control your metabolism. Makes sense when you put it together, huh? Sucks when it takes them a year though! Grrr. So before you start on a Powerade only diet, have that checked out too. And guess what is one of the best things ever? Pepto comes in mint flavored chewable tablets. They're fabulous! You can keep them in your purse! And then, a heat pad on the tummy is a wonderful thing too. Try that. Peppermint tea and a heat pad is heaven when you feel like your tummy is revolting against you. Hope this helps!
Lynn