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Traumatic Brain Injury and Post Concussion Syndrome For traumatic brain injury (TBI) and post concussion syndrome (PCS). |
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08-02-2014, 08:11 PM | #21 | ||
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If they are measuring plasma concentrations, the more plasma in a body, the lower the concentration for the same dose. Blood volume is directly proportional to weight.
All this data aside, what matters is how the person reacts to a specific dose of gabapentin. All the theory in the world will not over-rule how an individual responds. If plasma concentration peaks at 3 hours, I must be responding to a lower concentration. Maybe the higher concentration achieved later is what helps me sleep so soundly.
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08-03-2014, 12:59 AM | #22 | |||
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However, if considering two adults of about the same height and build, where one is skinny and one is rotund, I don't see it. Are you saying that if I, who weigh 140lb, were to put on another 140lbs, my plasma volume would double? [edited to add that I sort of answered my own question in the next post.] Quote:
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Also remember that we can feel effects sooner than peak -- might be your case. The helping to sleep is really individual. What helps whom depends a lot on why one is having difficulty sleeping. When I go to a sleep aid it's because I basically need a boulder dropped on my head. take care waves. Last edited by waves; 08-03-2014 at 01:27 AM. |
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08-03-2014, 01:26 AM | #23 | |||
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http://www.healio.com/orthopedics/jo...ons-in-obesity (The article discusses mostly drugs associated with orthopedic surgery, but it talks about the whys and the wherefores... and these are quite interesting, and diverse! ) Happy reading to anyone interested. |
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08-04-2014, 05:50 PM | #24 | ||
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12/02/2012 - Light concussion at boxing practice. Ended up having PCS for about 3 months. March 2013 - Thought that since most of my symptoms resolved I could start having fun again. Went snowmobiling once (didn't hit my head) and concussion symptoms returned and got even worse than before. June 2013 - accidentally bumped my head against a deck railing, and had a month-long setback. November 2013 - drove to work after a big snowstorm and the roads were very rough, ended up having another setback. 2014 - Having setbacks after coughing/sneezing too much, or someone slapping me on the back, or any other significant jarring. Feb 2014 - Started seeing Atlas Orthogonal chiro - most helpful doc so far. June 2014 - Two months of physical/visual therapy - no noticeable improvement. September 2014 - Diagnosed with Perilymph Fistula in right ear. November 2014 - Fistula surgery (switched to left ear before the surgery after additional testing). January 2016 - Quit work to "work" on figuring out PCS, so far it seems that eyes/vision issues are the most contributing factor, especially computer work. Current symptoms are: inconsistent sleep patterns, headaches, vertigo/dizziness, anxiety/panic attacks, mental fog/problems with concentration, problems with computer screens. |
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