May he rest in peace..... Dr. Bernard Bihari 1931-May,16,2010

Oh, no! Had he been ill? I haven't read alot about him but this is so sad.

I started my additional 1.5 mg dose today. I took my regular 4.5 dose at about 1 AM.....then my 1.5 dose about 11 AM. Haven't felt any different but wasn't really expecting to. I'll keep this up and see if I notice any improvement over the next month or so.

Okay, I've taken the additional 1.5 mg dose for 6 days. I noticed nothing different at first. After a couple of days my left leg started hurting (spasticity). Then my right hand/arm became very, very weak. This is the hand that has been numb for several years. I can still use it but it's hard to write and hard to grasp things. It got so weak that I couldn't even hold my hairbrush! I stopped the additional dosage and I can already tell a difference this morning. No leg pain and my right hand is working much better. Needless to say.....I'm not going to take the extra dose anymore!

Kelly, be sure to tell Doc S, so he won't think this idea of his worked.

I will. Hey, Sally.....does Dr. S have an email address? If he does can you PM it to me?

He suggested this increase in dosage after I told him about my bout of ON. He said if it were him he'd up his dosage of LDN. I asked if I got spasticity or any other negative sx if I could just stop the extra dose and he said yes. I got these same sx the first time I tried to go from 3.0 to 4.5 mg. After several tries I was able to tolerate the 4.5 dose. I could probably try increasing my dosage again and it might work.....but I really don't feel like I need any extra. The ON has completely cleared up (and quickly, too) and I feel really good on the 4.5 dosage.

Now, I just have some extra LDN should I ever run out!

Kelly, I don't have an e-mail for him, sorry.

I found that I heal a lot faster from occasional infections or illnesses, as well, with LDN.

Question..If exercise increases E production, how about taking LDN an hr pre workout? I'm going to try that tomorrow or Tues before I push my mile in wheelchair. I hate the drymouth at night and I drink about 1/2 gallon water/day plus not getting a solid nights sleep. Ive been on for almost 1 month and nothing yet...

I haven't done my mile since previous post. Been too hot, busy, got in pool yesterday for 1st time this yr, 93F right now so not today. Just got back from local monthly MS gathering. I said (when my turn came in the group circle,) "if exercise produces endorphines and LDN keeps me up at night, why not take it before workout?" Then said thats what i'm gonna do. They all nodded.

You are not understanding what LDN does for MS!! If you don't take it at night/early morn , when endorphines are reproducing themselves.... to temporarily block that reproduction, so that the body is fooled into increasing the rate of endorphine production, then LDN will, most likely, not work for you.

Good luck..