Do any of you ever experience twitching, spasms, feelings of heaviness and pulling the affected eye with Binocular MG? My left eye is almost constantly either twitching or feeling like worms are moving around the lower lid and temple area. The neuro-muscular neurologist I see at MUSC says it has nothing to do witht he OMG, except for the heavy/closing like feeling. I am on 20 mg of Prednisone daily now and CellCept 2 tablets twice a day. The Mestinon never really did help and I had the Infusions which had no positive affects as well. The pulling and twitching drives me crazy and affects my work (computer) and any reading I try to do. Any suggestions out there? My general practioner says that if any other symptoms come up that may go along with the twitching then he will explore it further. It really is annoying. I have been off the Mestinon for over a year now. Went through the high doses of Pred 60mg. daily and was out of work 3.5 months. The twitching, etc. has been going on now for about 2 months. Help!