Parkinson's Disease Tulip


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Old 07-17-2007, 08:02 AM #31
JoClay JoClay is offline
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Default I have noticed...

that I am receiving some benefit from the Azilect already. I have only been on this new medication (2 weeks of .5mg, and 1 week of 1.0mg) for a short time, but my gait has improved and I seem to be able to do things in less time. I walk faster, I am finishing my meals at the same time as everyone else at the table, and I have had no side effects that I can see. On the down side, it has done nothing for the tremor in my right hand, but I'll take what I can get. Hope others can get as much benefit as I am getting.
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Old 07-18-2007, 03:16 AM #32
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Quote:
Originally Posted by JoClay View Post
that I am receiving some benefit from the Azilect already. I have only been on this new medication (2 weeks of .5mg, and 1 week of 1.0mg) for a short time, but my gait has improved and I seem to be able to do things in less time. I walk faster, I am finishing my meals at the same time as everyone else at the table, and I have had no side effects that I can see. On the down side, it has done nothing for the tremor in my right hand, but I'll take what I can get. Hope others can get as much benefit as I am getting.
Maybe stiff, akinetic parkies get better results from Azilect than tremor-dominant ones. We're all so different, but I stand by what I said, I am having an overall improvement of my symptons (not sure about balance), to include better mood, plus a relief from levadopa-induced dyskinesia.
As you say, I finish my meals at the same time as everyone else.
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Old 12-06-2011, 02:52 PM #33
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Default Still rapturous over Azilect?

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Originally Posted by Teretxu View Post
Just when I thought that I had to accept my fate, my ever worsening symptons and crazy dyskinesia, thereby losing my personal autonomy of coming and going at my leisure, driving a car and having a social life, a little miracle has happened:

I was at the neuros' last week for the yearly follow-up of a nationwide study on YOPD which I am part of, and while going through the testing, my neuro noticed that I was far more dyskinetic and jittery than last year. It's probably the Stalevo, she said, and asked whether I had heard about Azilect (rasagiline). I said yes, but knew nobody taking it. It's something like a new generation of selegiline, but much improved.

Well, she gave me a prescription to try it (a blister with 30 1 mg-tablets). You take one (or half) in the morning and it lasts 24 hours. I simply could not believe it, half a tablet (0,5 mg) cuts it for me. I'm free of dyskinesia all day, my movements are much smoother and I can go out of the house whenever I want, without worrying about not being able to drive back or have a fit of dyskinesia in the wrong place at the wrong time.

It's as if I had turned back the time 3 or 4 years. I'm really happy with it.

Hugs to all and especially you fellow-dyskinetics!
I'm about to start Azilect; wondering how you feel about it after 4 years? Considering Comtan, and possibly Amantadine, to supplement 600mg Sinemet (10 years). Would appreciate your perspective.
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Old 12-10-2011, 02:32 PM #34
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I stopped taking Azilect when I saw the research that said it didn't slow the progression of the disease. I had several days of withdrawal, which I expected, and then my affected hand went south: pain, cramps, inability to write. I was exhausted and unable to focus. My doctor said it would take 4-6 weeks for the drug to be completely out of my system. After a little more than a month I gave up and went back on Azilect. Even the first day I felt a little better. After five days I feel nearly back to normal. I'm actually typing this at nearly normal speed. I thought the drug wasn't doing anything worth noting, but, in my case at least, it was/is doing a lot. (I was able to continue cycling while off the drug, but it was more difficult.)
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Old 12-15-2011, 11:49 AM #35
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Further update. I emailed my neuro and he suggested that instead of using Azilect, I raise my dose of ReQuip XL from 4 mg. to 6 mg. and stop the Azilect. I did that yesterday and not only did I need no afternoon nap, my tremor nearly stopped completely. My right hand and arm stopped hurting as well. I'm curious to see how this plays out for the long haul.
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