I wonder why some of us get so charged up on the RALA?

That fast absorption must go to the brain quickly..etc.

My evening dose doesn't seem to do it as much as the morning one. Maybe I am just getting used to it, too. I started at 50mg, back when, because of it, in fact.

Well I have cut my supplements in half after i realized I was sitting in the recliner bug eyed in perpetual anticipation that something big is about to happen
Then it doesn't

Many dont anticipate how powerful some supplements can be. Here is a quick story of a personal experience.

My girl friend had taken in a new flat mate who appeared totally normal and well adjusted until she started acting strange. She was convinced there were ghosts in the house and thought I was bringing them in

to make her happy I allowed her to perform a sort of exorcism which required her pushing down hard on my stomach and forcing whatever evil spirit was in me to the outside.

By now my girlf friend was getting a bit frightened .

During the night My G/F went to go to the bathroom but something was obstructing the bedroom door. It was the flatmate lying in the hall surrounded by candles at 2am ( hard to imagine i know ), well now I was starting to get scared myself so we called her family who took her to the nearby hospital because she was Babbling and hallucinating

She ended up in the psychiatric ward and after much investigation they found the culprit......Chinese medicine/herbs! turns out she misread the dose and was taking 10 x what she should.

After she stopped the herbs she returned to normal.

If I hadn't witnessed it myself i never would have believed how powerful supplements can be.

Wow, you have to be responsible. Natural meds are the first medicines. They work.

They certainly do. I guess its no different to eating to many hash or marijuana cookies which could also bring on hallucination

We still have a good laugh about that night though

Glad all turned out ok!

I would be more worried about the drugs a doctor prescribes, and the dosages recommended on over the counter drugs. Particularly those for pain. When it says you can take 2 pills every four hours, many folks blindly do that and then they will always need that high dose. Not to mention the organ damage, but somehow we have changed the subject.

I have begun taking the stabilized R Lipoic one pill on the empty stomach as recommended.

You bring up an excellent point, stillfighting!

Dr. Jay Cohen, believes that many drugs are used in too high of doses. In fact he thinks the drug companies patent high doses on purpose! It is in his cholesterol book and also on his website in
shorter version...

He has a new book out on the subject too!
http://www.lef.org/Vitamins-Suppleme...Over-Dose.html

For example, Crestor, which is typically given in doses of 10mg and above....works in 1mg doses. There is a new PubMed article on 5mg Crestor given once or twice a WEEK as working!
So this new paper from 2012 illustrates that much less Crestor works as well as high dose (with its toxicity profile risks).

http://www.ncbi.nlm.nih.gov/pubmed/22256801

I find that 1/2 of a tramadol 50mg works for me most nights in fact! That is 25mg... I don't take it every day, so I have not tolerance to it yet.

That sounds like it could also be just melatonin. That would account for the seasonal change as daylight shortens and the large meals containing more tryptophan (and other enzymes).
Doc

I've been saying that for some time (long before these examples), but phrased slightly differently:
I won't argue that this has been intentional, and even misleading, in some cases, like the highly publicized Oxycontin case,
but I think it more likely began in the attempt to find average dosing recommendations for doctors who aren't well-versed in pharmacology.

Doc

Ok, I started the new improved fancy-schmancy "stabilized" RLA this week. The plan was to wait until I had used up current supplies of the old-fashioned unimproved unstable (does that mean it's explosive? ) flavor, but after discussions with DW it was decided I'd take the new one in the morning and the old one in the evening (in case there is some kind of "speed" factor...)

When I started the regular old flavor RLA (about a year ago), I got phenomenal results in just 48 hours. So far, I've been on the new regimen for about 72 hours, and haven't noticed anything at all... No biggie - it's probly too soon, and I shouldn't/wouldn't (but could! ) expect lightning to strike twice...

Got back on B5 after an unintended month off and noticed a significant difference in just a few days, but this is the wrong forum for that...

Doc