Hi,
I got really sick on a Thursday night. Fever, headache, sore throat. I was tested for step and it was negative, however, my throat was SO bad I was given Clindamycin and within 24 hours I had sever tingling, burning and pins in needles in hands and feet. I went back to the DR the next day and they gave me Amoxocillan. I took that for a day and am now stopping all antibiotics as it seems to be getting worse.

I can barely walk and my hands that were fine yesterday are now starting to break out in red blotches. I started researching and that landed me here. Has anyone had something like this happen? Is this permanent? What type of DR should I see? Does this sound like the result of the antibiotic?

I'm not sure what to tell work as I am still very sick from the original issue but now I can hardly walk with this new issue.

Any thoughts are greatly appreciated.

That is very unusual to give Clindamycin for a sore throat.

Are you sure it wasn't ciprofloxacin?

Cipro and other fluoroquinolones can cause nerve damage.

Did you take any antihistamines? In case it is an allergic reaction?

Staph infections can cause a severe sore throat. And so can viruses. Epstein Barr which is the mono virus causes a severe sore throat in some people. Antibiotics typically do not work for it, unless a secondary infection occurs. Did they do a mono-spot test on you to see if you have mononucleosis?

Hi,
I am sure it is Clindamycin. They did not test me for Mono but the sore throat is not going away and it's the worst I've ever seen. They did the strep test and it came back negative but he elected to give me an antibiotic anyway as I was SO sick. He want to try Clindamycin because he said Amoxicillian can give a rash or something like that. I really didn't want to try something I had never tried but I went with his recommendation.

Within 24 hours, my hands and feet were burning up, pins and needles and I could hardly walk. It came on very, very quick.

Is there any information out there? Will this clear up quickly? Is this permanent? It's possible I have Mono and then the antibiotic combination caused this issue. I'm not even sure what type of Dr to see?

Please let me know any info at all?

When an antibiotic is given for a viral infection.... sometimes a rash appears...it is called a viral exanthem.

You can Google that term.

PN does not occur so fast as a rule. It can following use of fluoroquinolones..like Cipro. But not as often with other antibiotics.

The symptoms of PN may occur independently of actual nerve damage... which is another form of PN. Sometimes it is difficult to separate out "parestheisas" or symptoms, from real damage.

In your favor is time. Infectious events are often confusing and there is no real answer for you so quickly. When you get upset and super stressed, those symptoms can seem bigger. We all know this on this forum. So try to relax a bit...and see what develops.

Thank you for the replies. When it presented it was extreme burning on hands and feet, severe pins and needles, feet feel hot to the touch. After about a day, I do see a very slight red rash that looks like it's coming from the inside out, almost like small blisters. Does that not sound like PN?

I did read on parestheisas but it basically sounded the same as PN? Would I go see my primary DR regarding this issue or a special DR? Does parestheisas generally clear? I for sure need a mono test as I'm pretty sure what I have is viral. I'm totally off antibiotics for about 12 hours now but it's not getting any better.

Is parestheisas temporary or can it be permanent as well? What kinds of Dr's know about this issue?

I get small fluid filled blisters on mucus membranes from ALL antibiotics...starting deep in the throat/airways and working it's way out. I have never talked to anyone who has had a similar type reaction...until you. Is it affecting your breathing at all? My reactions will drop my O2 saturation from my normal of 98 down to as low as 91. It causes an awful sore throat as well.

My blisters take at least a week to reduce and feel better (longer to completely go away) after stopping the antibiotic.

I wonder if your PN and blister reaction is an autoimmune response. PN from autoimmune disease can cause rapid onset. An it's quite common for autoimmune disease to be trigger by an infection (viral or bacterial). My antibiotic reaction is thought to be related to my autoimmune disease, Sjogren's.