The methylation testing will show if you have mutations that lead to heart disease. The COMT along with the MTHFR, is thought to lead to heart/circulation problems.

This explains better than I can:
http://doccarnahan.blogspot.com/2013...-big-deal.html

The bottom line is that if you have this problem you need methylfolate, and methylcobalamin and perhaps balance some other B's like niacin.

Here is another:
http://mthfr.net/

You can get the test online, for $99 but you have to interpret your results yourself as the FDA has blocked that function for us...nice eh?

It is turning out that the people arriving here and getting this testing are all showing various mutations that seriously affect health.

Back to your list. The Curcugel could now be replaced by the new better curcumin... CurcuBrain by NOW. This has the optimized enhanced absorption developed by LongVida and is actually better that Curcugel, now.. and similar in price. It is available on Amazon. This is the one I am currently using.