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What is the difference between SFN & PN?

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Old 08-18-2015, 10:56 AM #11
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Originally Posted by Healthgirl View Post
Also peripheral neuropathy is distal, where SFN can be non length dependent. It can be all over your body and face. Like me
Indeed, nothing like burning ears and a tingly jaw eh?
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Old 08-18-2015, 11:35 AM #12
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Small Fiber is just a form of neuropathy. It is peripheral as well. There are other forms that affect the large fibers and motor function. Small fiber usually results in pain, burning, tingling, buzzing, numbness, etc. You also might want to look up autonomic neuropathy which can cause some of the other issues you mentioned.

Have you had extensive blood work done? Testing for diabetes, thyroid, toxicity, vitamin levels, autoimmune issues, etc. ? That would be essential now that you have a confirmed diagnosis. A good neuro will want to search for the cause of SFN, once its diagnosed. A skin biopsy is pretty accurate in diagnosis SFN.
I have had numerous blood tests. I have an incurable bladder disease and drs. thought it might all be related. Systemic
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Old 08-18-2015, 11:40 AM #13
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What are your symptoms in your left arm and leg? That is where mine started too.
Mine started in my groin area, my left pinky and left foot toes. Both feet had numbness but, my left foot is VERY weak. Now my hand shakes and my leg shakes. Sometimes my shoulders shake. I have muscle jumping all over. Especially when I'm anxious or tired. I'm also having bowel problems and terrible pressure in upper abs and back.
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Old 08-18-2015, 11:58 AM #14
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I have had numerous blood tests. I have an incurable bladder disease and drs. thought it might all be related. Systemic
Were you on any medications long term recently like Acid controlling drugs or statins?
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Old 08-18-2015, 12:03 PM #15
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Women who have IC symptoms should consider if they use Lisinopril for blood pressure.

This drug is excreted whole, and irritates the bladder lining. It causes a buildup of Bradykinin which swells the tissues of the bladder and irritates it.

Also looking at a low oxalate diet may help.
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Old 08-18-2015, 01:15 PM #16
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Also peripheral neuropathy is distal, where SFN can be non length dependent. It can be all over your body and face. Like me
I don't understand.....distal and non length dependent?
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Old 08-18-2015, 01:19 PM #17
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Were you on any medications long term recently like Acid controlling drugs or statins?
I was on the only drug used to help rebuild the bladder lining, Elmiron. I stopped using it after 6 months because of digestive issues and half my hair fell out. My GI doc said stomach issues were the number one complaint with Elmiron.
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Old 10-03-2015, 07:00 PM #18
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Originally Posted by Healthgirl View Post
Also peripheral neuropathy is distal, where SFN can be non length dependent. It can be all over your body and face. Like me
All clinical studies I've found agree that Alcohol PN begins distall, but if the obvious necessary behavioral changes are not addressed within a timely window, the worsening PN will progress in proximal direction.
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