QSorry to hear you're having a hard time. I don't know if I have motor issues as well as sensory. The only thing I can attribute to motor sensations is the muscle pulling type twitches I get at night. They are not the leg jerking sensations you describe and mine right now are much less then you describe but I will gladly give you my input.

I like the Aspercreme Lidocaine that MrsD mentioned in her post for the burning. It stopped my pre-twitching one night after I applied it. I also like Mortons Lotion. Instead of B1 I take Benfotiamine. I also take Manganese, Slow Mag, B12 Methylcobalamin sublingual, Folic Acid, Omega 3, B complex, Vitamin C and D3. I am on 300mg Gabapentin at night. Even at this low dosage I had side effects immediately but after about 2 weeks my body adjusted. I have never done well with prescription drugs.

Most of these vitamins i have been taking for many months, but some are more recent based on the results I got from the Spectracell Blood Test for Vitamins and Minerals.

My sensations have gotten much more manageable the last 2 months. I wish I could definitively say what has helped the most but it has been impossible to conduct a real scientific type study when I was suffering and just wanted it to stop.

I think the Lidocaine, Morton's lotion, Slow Mag, Benfotiamine and Gabapentin have probably been the most useful for helping the symptoms you describe. However I can't be sure as there is a reason behind every supplement I take. Of course what is working for me doesn't mean it will work for you. It doesn't even mean if will work for me tomorrow! Hope this helps. You can pm me if you have questions.