Dear Denny,
I tried Savella for almost 2 months. My Rheumatologist (who I was trying to get a new opinion and a new perspective on CRPS) told me it was related to Cymbalta (which I had already tried and it had made me an insomniac so I was told to get off of it), but considered it to be better since it was developed later when doctors understood more about antidepressants. I am fairly sensitive to medications as well. I started out at 12.5mg and soon found that I could not handle anything over 12.5mg 2x/day because I would get so nauseous I wouldn't be able to eat. Also, whenever I tried increasing it, I felt like my burning pain would increase. It is hard to say; it could have been coincidental since my burning pain often goes up and down for no reason. Anyways, after losing weight and still not becoming accustomed to it, I dropped the med. If you do try it, I really hope it works for you! Please let us know how it turns out.