I am taking only 25mg of atenolol. I used to take this years ago but then my doctor wanted to put all her patients on the ACE inhibitors! At first I had no problem. It seems in the past 2 yrs the edema was creeping up. So then she gave me Lasix which I use once a week or every other week. Then BOOM... I had a huge full body attack and my pelvic area swelled up so badly I couldn't sit...it hurt so much. I was huffing and puffing breathing and very weak and my blood pressure was higher than ever. This I think is from the stress of it all, and due to cortisol released to help with the stress.

I took the lisinopril at night and would wake up 3 hrs later in terrible pain in the bladder and everywhere else....it would go away until the next afternoon, then I would have dinner, and take the next lisinopril and boom again... So I looked at what I was taking at night... Benadryl, Vit D, melatonin and lisinopril and a light bulb went off in my head and I just stopped it and called my doctor.

I use the Morton's Magnesium Epsom lotion to take down the swelling, and it combined with the atenolol to bring my uncontrolled 180/100 down to 135/70!

I guess my system stopped degrading the bradykinin, and it built up to massive levels and caused all the grief. I also had terrible abdominal pain with this, it felt at times like I was going to "burst"... the whole reaction is settling down now. The bromelain is really helping and I can get into my older underwear again!
This clothing problem was very embarrassing, and I had to order special old lady underwear with no elastic online! I couldn't wear any of my clothes for at least 2 weeks either.

My hands still swell, but they go down if I rub in the mag lotion on the backs and wrists.

If you search bradykinin, there are papers explaining that repetitive motion will trigger angioedema attacks. So typing here must be causing my hands to swell, as well.

The edema takes a while to come down. And if you have the hereditary type, or the estrogen acquired type, you may still have some remaining edema, anyway. But now for me it has been just over 4 months, and I am a new person!

If your doctor has not had the CE on this topic like my internist...print out those two sites I gave you...as they target doctors with the information.

One characteristic of this is a type of skin swelling is called peau d'orange. This is where the individual pores are visible on the area and it resembles orange skins. Mine was most noticeable on my forearms (where my lupus skin discoloration is), and upper thighs. It is sort of like cellulite, only more uniform in appearance.
The magnesium lotion really shrinks this orange skin up, for me.

Type into Google hereditary angioedema and select images.
There are photos showing one leg or one hand, swelling. Some facial swelling. I had lower lip swelling and tongue enlargement too. I still get the lip thing moderately, but my tongue is much better, and I can taste things better too.

You should really get the blood work done, to rule out HAE for yourself... those complement, and C-inhibitor levels are diagnostic. They are on the HAE website.