Just choked on my water on this one. Long story short, when the neuro and I decided meds were not going to be the route for the spasticity for me she sent me to PT. The PT was young and just out of college. I was explaining my experience with the meds and told her that as a child of the 60's and 70's I apparently didn't do enough drugs. Couldn't tolerate it. LOL

Definitely as interesting point tkrik. Just how do they know?

We could have a 250 lb man taking "C" and a 125 lb women. Is the fat level the same for injection distribution purposes?

Or what about one who metabolizes an oral drug quickly, and maybe one who absorbs drugs slowly. The ideas on this are endless.
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Speaking of "C", there is a new clinical trial on "C". It will consist of two different formulations. Maybe pain and injection site reactions will be stopped.

Safety of New Formulation of Glatiramer Acetate (Song)

Purpose

The purpose of this study is to compare injection-site reactions and pain associated with injections of the approved formulation of Glatiramer Acetate (GA) versus investigational formulation of GA. In addition, the investigators will evaluate the side effects of the two formulations of GA.

Study Start Date: July 2009
Estimated Study Completion Date: November 2009
Estimated Primary Completion Date: November 2009 (Final data collection date for primary outcome measure)

http://www.clinicaltrials.gov/ct2/sh...s=teva&rank=15

http://www.thisisms.com/downloads/Co..._Other_Day.pdf

Cherie

Thanks both Lady's. I read them both and will be talking to the neuro about them when I go. I don't mind doing the C everyday if that's what I need to do in this crap shoot but I do mind the toxic feeling.

When DD19 was a wee little one she had to have some dental work done. She was about 2. She had terrible teeth and they attributed it to her being such a big baby at birth. Poor thing. Anyhow, they gave her Demerol and quite frankly I called it Demonall. She got so out of hand that they asked me if I wanted to come back another day or put her in a restraint. I chose the restraint. I was not going through that again. This was her 2nd time with this stuff.

Anyhow, the point this "story" is that the dentist told me that sensitivities to medications tends to run in families. I thought that was interesting as most of my family is that way. DD19 is still that way yet DD17 is not that way. She can tolerate far more that I.

I am very sensitive to meds too, T.

My daughter had baby teeth problems too, cause her body was eating the roots from the bottom up. All that was left was the crowns by the time she was about 5, and they fell out piece by piece. Thankfully her adult teeth are good, well except the braces part. (I had to have her knocked out at a hospitial at age three, to have 11 root canals done!).

Remember, those are small studies and your doc might not be too keen ... but given that Rebif and Avonex have very similar efficacy, yet they are really just 1/2 (or twice) the dosage of the same drug, I believe variances in dosage is probably gonna be ok with all the drugs. JMHO

Cherie