[lg4fun]

Hi,
I got really sick on a Thursday night. Fever, headache, sore throat. I was tested for step and it was negative, however, my throat was SO bad I was given Clindamycin and within 24 hours I had sever tingling, burning and pins in needles in hands and feet. I went back to the DR the next day and they gave me Amoxocillan. I took that for a day and am now stopping all antibiotics as it seems to be getting worse.

I can barely walk and my hands that were fine yesterday are now starting to break out in red blotches. I started researching and that landed me here. Has anyone had something like this happen? Is this permanent? What type of DR should I see? Does this sound like the result of the antibiotic?

I'm not sure what to tell work as I am still very sick from the original issue but now I can hardly walk with this new issue.

Any thoughts are greatly appreciated.

[mrsD]

That is very unusual to give Clindamycin for a sore throat.

Are you sure it wasn't ciprofloxacin?

Cipro and other fluoroquinolones can cause nerve damage.

Did you take any antihistamines? In case it is an allergic reaction?

Staph infections can cause a severe sore throat. And so can viruses. Epstein Barr which is the mono virus causes a severe sore throat in some people. Antibiotics typically do not work for it, unless a secondary infection occurs. Did they do a mono-spot test on you to see if you have mononucleosis?

[lg4fun]

Hi,
I am sure it is Clindamycin. They did not test me for Mono but the sore throat is not going away and it's the worst I've ever seen. They did the strep test and it came back negative but he elected to give me an antibiotic anyway as I was SO sick. He want to try Clindamycin because he said Amoxicillian can give a rash or something like that. I really didn't want to try something I had never tried but I went with his recommendation.

Within 24 hours, my hands and feet were burning up, pins and needles and I could hardly walk. It came on very, very quick.

Is there any information out there? Will this clear up quickly? Is this permanent? It's possible I have Mono and then the antibiotic combination caused this issue. I'm not even sure what type of Dr to see?

Please let me know any info at all?

[mrsD]

When an antibiotic is given for a viral infection.... sometimes a rash appears...it is called a viral exanthem.

You can Google that term.

PN does not occur so fast as a rule. It can following use of fluoroquinolones..like Cipro. But not as often with other antibiotics.

The symptoms of PN may occur independently of actual nerve damage... which is another form of PN. Sometimes it is difficult to separate out "parestheisas" or symptoms, from real damage.

In your favor is time. Infectious events are often confusing and there is no real answer for you so quickly. When you get upset and super stressed, those symptoms can seem bigger. We all know this on this forum. So try to relax a bit...and see what develops.

[lg4fun]

Thank you for the replies. When it presented it was extreme burning on hands and feet, severe pins and needles, feet feel hot to the touch. After about a day, I do see a very slight red rash that looks like it's coming from the inside out, almost like small blisters. Does that not sound like PN?

I did read on parestheisas but it basically sounded the same as PN? Would I go see my primary DR regarding this issue or a special DR? Does parestheisas generally clear? I for sure need a mono test as I'm pretty sure what I have is viral. I'm totally off antibiotics for about 12 hours now but it's not getting any better.

Is parestheisas temporary or can it be permanent as well? What kinds of Dr's know about this issue?

[en bloc]

I get small fluid filled blisters on mucus membranes from ALL antibiotics...starting deep in the throat/airways and working it's way out. I have never talked to anyone who has had a similar type reaction...until you. Is it affecting your breathing at all? My reactions will drop my O2 saturation from my normal of 98 down to as low as 91. It causes an awful sore throat as well.

My blisters take at least a week to reduce and feel better (longer to completely go away) after stopping the antibiotic.

I wonder if your PN and blister reaction is an autoimmune response. PN from autoimmune disease can cause rapid onset. An it's quite common for autoimmune disease to be trigger by an infection (viral or bacterial). My antibiotic reaction is thought to be related to my autoimmune disease, Sjogren's.

[lg4fun]

Hi En Bloc,
This could definitely be related to something autoimmune. Autoimmune issues run in my family. Based on some of the feedback from mrsD, I'm thinking I have a really bad case of Mono or some other viral type sickness (going to the DR today). I think the antibiotic along with the virus has produced some secondary issues. The worst one is this issue with my hands and feet. Is your issue in your mouth only or do you get it other places? How long does it take to clear up after you stop taking the antibiotic? Any info you can share would be great.

My throat and tonsils are a mess. My hands and feet are now also a a mess. It started out as burning sensation, moved to severe pins and needles and I am on day three and can still hardly walk. I do have some red bumps coming up as well on both hands and feet. Initially, I was not sure if this was toxicity to the antibiotic that caused nerve damage or something else. I have had nerve damage in the past when sick. 8 years ago I also got really sick and ended up with Bells Palsy, right side of my face paralyzed as the nerve had been damaged by the illness. I recovered quickly but it took about 4 weeks.

Now I may have something like Mono and my hands and feet are not paralyzed but something is seriously wrong. I don't know enough about NP, Parathesia or even the viral exanthem to understand what I might really be dealing with. There is not much out there on them that gives good information.

[mrsD]

GBS is fast onset, and accompanies a viral illness or vaccine exposure.

Not always has a rash though.

http://www.cdc.gov/flu/protect/vacci...llainbarre.htm

GBS can also follow from food poisoning from uncooked chicken infected with Campylobacter bacteria.

A neighbor of mine developed GBS following chemo for breast cancer treatment. She had a spring virus, and within days couldn't walk. It did spare her breathing however. She had plasmapharesis treatments to remove the offending immune peptides from her blood.

So if you develop any breathing problems, seek medical attention ASAP.

[lg4fun]

Okay, so this is unreal. After all of this, the issue has been deteremined. I have hand, foot and mouth virus!! I had not even heard of this until now. It starts with fever, really bad sore throat, headache.. After a few days, a rash forms on the hands and feet and often the mouth (which I didn't get). It just so happens that this formed about 24 hours after being on Clindamycin and then Amoxocillan. I thought maybe it was the antibiotic but with this virus I would have gotten this without them as well.

I got this from a one year old who stayed at my house a few weekends ago. She had small blisters on her hands and feet and I asked the mother if she had eczema and was told no but no mention of this virus. The baby seemed fine as she must have been past it. Adults normally do not get this but I've often been easily affected by virus's. Something with my immune system I guess :/

Soooo, this has been quite a process. The information provided through this board helped me out a lot. I so appreciate the replies and the assistance. Can't believe this one...