It's not a drug to play with, primarily used for bone cancer patients. It is a bisphoshonate drug which is under investigation for use in RSD patients. My doctor stopped using it after my reaction and there is no clear evidence that it works for RSD.

Like I said I had a very severe allergic reaction to it, more than the flu like symptoms that's described in the attached document describing it. http://www.cancercare.on.ca/common/p...x?fileId=10683 I Know there is a study out there about it's affects on RSD patients but I can't find it right now.

I lost my hearing partially in one ear, the blood vessels in my opposite eye all burst and I have a permanent ringing noise, sometimes loud, in my head that makes it difficult for me to hear especially when there is any type of background noise. That being said I did have a temporary reprieve from the deep bone pain I initially complained about. Was it worth it NO! I'm not able to take any other drug in that class, I was taken off all the osteoporosis drugs and can't try any new ones. Not good news for an RSD patient who isn't even yet past menopause.

It was the second infusion that took me over the edge and landed me back in emergency at the same hospital I received the infusions. I ultimately had to resort to a doing a "sit in" at the waiting room of the ENT clinic insisting that the head of the department see me so I could get some help. The emerg department had released me with a shrug of their 3rd year resident shoulders claiming it was merely a migraine. I suffer from migraines so I knew that there was much more to it than just that and I was really sick and scared.

I did get help ultimately, including oral steroid, steroids injected directly into my ear drum and HBOT. The loud explosive motor sound is now down to a low buzzing noise that no longer makes me want to cut my ear off. I now know why Van Gogh did that, it had nothing to do with him being crazy, it's said that he suffered severe tinnitus too and it is that relentless sound that drives one crazy. I'm so grateful it has subsided to a dull roar.

I wish you well with your up coming appointment, please let us all know how it goes for you. I just can't recommend this particular drug.

MsL